Author

Amy Burley

Institute of Cancer ResearchORCID 0000-0003-3074-6439Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1

Frequent Co-Authors

Alan A. MelcheriD· 3 shared Anna Clare WilkinsiD· 3 shared Katie O’FeeiD· 2 shared Kevin Joseph HarringtoniD· 2 shared Malin PederseniD· 2 shared Nicholas David JamesiD· 2 shared Tatiany Silveira· 2 shared Tom LundiD· 2 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

Alan A. MelcherORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 22, 2026

Spatially-resolved multimodal profiling identifies functionally-heterogeneous cancer-associated fibroblasts associated with poor radiotherapy outcomes in muscle-invasive bladder cancer.

Amy Burley, Katie O’Fee, Morgane Dromby…·Anna Clare Wilkins

This study identifies functionally heterogeneous cancer-associated fibroblasts in muscle-invasive bladder cancer linked to poor radiotherapy outcomes.

DOI 10.64898/2026.09.18.752662

mousebulk RNA-seq

𝕏 PostBluesky

PathologybioRxivPreprintJul 1, 2026

Development of a multiplex immunofluorescence panel to study heterogenous cancer-associated fibroblast subtypes with spatial resolution

Amy Burley, Tatiany Silveira, Nicholas David James…·Anna Clare Wilkins

1 citation

humanimaging

𝕏 PostBluesky

Cancer BiologybioRxivPreprintMar 18, 2026

Addition of chemotherapy to radiotherapy promotes progenitor-exhausted CD8+ T-cell clonal dominance in head and neck cancer

Charleen Chan Wah Hak, Anton Patrikeev, Antonio Rullan…·Alan A. Melcher

This study shows that chemoradiotherapy (CRT) in head and neck cancer promotes clonal dominance of progenitor-exhausted CD8+ T-cells compared to radiotherapy alone.

DOI 10.64898/2026.03.10.710795

mousescRNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintOct 7, 2025

Rapid expansion of podoplanin-positive fibroblasts following radiation limits the anti-tumour CD8+ T-cell response to radiotherapy.

Anna Clare Wilkins, Spyridon Makris, Mary J. Green…·Erik A. Sahai

This study shows that radiation-induced podoplanin-positive fibroblasts limit CD8+ T-cell access to tumour cells, reducing radiotherapy effectiveness, and that disrupting PDPN signaling enhances tumour control.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky