Author

Anna Clare Wilkins

Royal Marsden NHS Foundation TrustORCID 0000-0002-0425-584XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Assay:imaging· 1

Frequent Co-Authors

Amy BurleyiD· 3 shared Alan A. MelcheriD· 2 shared Katie O’FeeiD· 2 shared Nicholas David JamesiD· 2 shared Tatiany Silveira· 2 shared Tom LundiD· 2 shared Adrian LärkerydiD· 1 shared Ananya ChoudhuryiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersCancer Biology

Amy BurleyORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 22, 2026

Spatially-resolved multimodal profiling identifies functionally-heterogeneous cancer-associated fibroblasts associated with poor radiotherapy outcomes in muscle-invasive bladder cancer.

Amy Burley, Katie O’Fee, Morgane Dromby…·Anna Clare Wilkins

This study identifies functionally heterogeneous cancer-associated fibroblasts in muscle-invasive bladder cancer linked to poor radiotherapy outcomes.

DOI 10.64898/2026.09.18.752662

mousebulk RNA-seq

PathologybioRxivPreprintJul 1, 2026

Development of a multiplex immunofluorescence panel to study heterogenous cancer-associated fibroblast subtypes with spatial resolution

Amy Burley, Tatiany Silveira, Nicholas David James…·Anna Clare Wilkins

1 citation

humanimaging

Cancer BiologybioRxivPreprintOct 7, 2025

Rapid expansion of podoplanin-positive fibroblasts following radiation limits the anti-tumour CD8+ T-cell response to radiotherapy.

Anna Clare Wilkins, Spyridon Makris, Mary J. Green…·Erik A. Sahai

This study shows that radiation-induced podoplanin-positive fibroblasts limit CD8+ T-cell access to tumour cells, reducing radiotherapy effectiveness, and that disrupting PDPN signaling enhances tumour control.

1 citation

humanbulk RNA-seq