Author

Chloe L Fisher-Ward

Guy's and St Thomas' NHS Foundation Trust

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:database / resource· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Adrian M. IsaacsiD· 2 shared Alexander J. CammackiD· 2 shared Mireia CarcoléiD· 2 shared R. NairiD· 2 shared Thomas J. CunninghamiD· 2 shared Adam CaulderiD· 1 shared Alfredo IacoangeliiD· 1 shared Ali R Awan· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersNeuroscience

Adrian M. IsaacsORCID

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2 papers

Recent·Most cited

CRISPR/Cas9-mediated generation of a de novo C9ORF72 knock-in isogenic iPSC cell bank to model ALS and FTD

Niamh Louise O’Brien, Erin C. Hedges, R. Nair, Alexander J. Cammack, Mireia Carcolé, Deniz Vaizoglu, Sara Tacconelli, K. Sutherland, Chloe L Fisher-Ward, Ali Raza Awan, Simon D. Topp, Alfredo Iacoangeli, Adrian M. Isaacs, Thomas J. Cunningham, Marc‐David Ruepp, Sarah Mizielinska

The paper generates isogenic iPSC lines with a C9ORF72 G4C2 repeat expansion to model ALS and FTD, showing both loss- and gain-of-function pathologies.

bioRxiv · Nov 12, 2025 · PreprintNeuroscience

Generation of C9orf72h370 mice, an intron 1 humanised C9orf72 repeat-expansion knock-in model

R. Nair, Mireia Carcolé, David Thompson, Charlotte Tibbit, Ross McLeod, Alexander J. Cammack, Tatiana Jakubcova, Daniel Biggs, Matthew Wyles, Matthew T Parker, Adam Caulder, Lydia Teboul, Chloe L Fisher-Ward, Ali R Awan, Michael D. Flower, , Thomas J. Cunningham

The paper generates a mouse model with a humanised C9orf72 repeat expansion to study ALS and FTD, and demonstrates a method for creating such repeat expansions in genomic sequences.

bioRxiv · Feb 6, 2025 · PreprintMolecular Biology