Dissociable control of motivation and reinforcement by distinct ventral striatal dopamine receptors
Juan Enríquez-Traba, Miguel A. Arenivar, Héctor E. Yarur, Chloe Noh, Rodolfo J. Flores, Tenley A. Weil, Snehashis Roy, Ted Björn Usdin, Christina T. LaGamma, Huikun Wang, Valerie S. Tsai, Damien Kerspern, Amy E. Moritz, David R. Sibley, Andrew Lutas, , Hugo A. Tejeda
This paper identifies distinct roles of dopamine D3 and D1 receptors in regulating motivation and reinforcement in the nucleus accumbens, showing compartmentalized signaling within the same cell type.
Nature Neuroscience · Dec 9, 2024Peer-reviewedNeuroscience