The Gq/11 family of Gα subunits is necessary and sufficient for lower jaw development
Stanley M. Kanai, Chloe R. Garcia, MaCalia R. Augustus, Shujan A. Sharafeldeen, Elliott P. Brooks, Juliana Sucharov, Ezra S. Lencer, James T. Nichols, David E. Clouthier
The paper shows that Gq/11 signaling mediates lower jaw development in zebrafish by restoring jaw structures and gene expression in Edn1-deficient embryos.
Development · Apr 2, 2025Peer-reviewedDevelopmental Biology