Elliott P. Brooks

This study shows that conditional ablation of PDGFRα and SHP2 in mouse neural crest cells leads to craniofacial defects, with SHP2 regulating PDGFR signaling both positively and negatively.

The paper shows that Gq/11 signaling mediates lower jaw development in zebrafish by restoring jaw structures and gene expression in Edn1-deficient embryos.

This study identifies KLF4 as a novel factor that cooperates with NKX2.2 to regulate alpha cell identity by co-occupying promoters and modulating chromatin accessibility.