James T. Nichols

Pax9 governs anterior identity and deployment of sclerotome to the median fins

This study shows that Pax9 is essential for anterior identity and proper deployment of sclerotome cells in the caudal fin of zebrafish, leading to fusion with the anal fin and altered skeletal development.

The Gq/11 family of Gα subunits is necessary and sufficient for lower jaw development

The paper shows that Gq/11 signaling mediates lower jaw development in zebrafish by restoring jaw structures and gene expression in Edn1-deficient embryos.

TFAP2 paralogs regulate midfacial development in part through a conserved ALX genetic pathway.

The paper shows that TFAP2 paralogs regulate midfacial development via the ALX genetic pathway in mice and zebrafish.

Variable paralog expression underlies phenotype variation

The paper investigates how variable expression of paralog genes underlies phenotypic variation in zebrafish craniofacial development.

Transgene-mediated skeletal phenotypic variation in zebrafish

The paper investigates how a chromosomally integrated transgene enhances specific phenotypes in fras1 mutant zebrafish, showing genetic partial dominance and locus-specific effects.