Author

Chloe S. Larson

Rockefeller University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

J. Fraser Glickman· 1 shared Jazmín Alarcón‐EspósitoiD· 1 shared Li GaniD· 1 shared Loreto Carvallo-Torres· 1 shared Ravi Kumar Nagiri· 1 shared Siyu WangiD· 1 shared Subhash C. SinhaiD· 1 shared Vipin Kumar Singh· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperNeuroscience

J. Fraser Glickman

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1 paper

Recent·Most cited

High-Throughput Screening and Initial SAR Studies Identify a Novel Sub-micromolar Potent Human cGAS Inhibitor

Jazmín Alarcón‐Espósito, Ravi Kumar Nagiri, Siyu Wang, Chloe S. Larson, Loreto Carvallo-Torres, Vipin Kumar Singh, J. Fraser Glickman, Li Gan, Subhash C. Sinha

The paper identifies a potent human cGAS inhibitor through high-throughput screening and SAR analysis, showing sub-micromolar activity and partial inhibition of cGAMP levels.

ACS Chemical Biology · Nov 18, 2025Peer-reviewedNeuroscience