NeuroscienceACS Chemical BiologyPeer-reviewed
High-Throughput Screening and Initial SAR Studies Identify a Novel Sub-micromolar Potent Human cGAS Inhibitor
Jazmín Alarcón‐Espósito, Ravi Kumar Nagiri, Siyu Wang…·Subhash C. Sinha
The paper identifies a potent human cGAS inhibitor through high-throughput screening and SAR analysis, showing sub-micromolar activity and partial inhibition of cGAMP levels.
2 citations