Vancomycin impairs macrophage fungal killing by disrupting mitochondrial morphology and function
Ebrima Bojang, Lozan Sheriff, Emma Morris, Sophie Rouvray, Man Shun Fu, Chloe Wellings, Ketema Abdissa, Victoria Stavrou, Callum Clark, Andrew D. Southam, Warwick B. Dunn, David Bending, José R. Hombrebueno, Ilse Denise Jacobsen, Sarah Dimeloe, , Rebecca A. Drummond
This study shows vancomycin impairs macrophage fungal killing by disrupting mitochondrial function and morphology, independent of microbiome effects.
mBio · Apr 29, 2026Peer-reviewedImmunology