Deciphering epileptogenic and activity-dependent gene programs in the human brain
Qianyu Lin, Chris J. Kang, André Machado Xavier, Irene Sanchez-Martin, Ashesh D. Mehta, Lucas Cheadle
The paper identifies activity-dependent gene programs in human epileptic brain tissue and finds that some responses are conserved with acute stimulation, while others suggest metabolic and inflammatory dysregulation in epilepsy.
bioRxiv · Feb 18, 2026 · PreprintNeuroscience