NeuroscienceNeurotherapeuticsPeer-reviewed
Discovery of an APP-Selective BACE1 Inhibitor for Alzheimer's Disease
Jesus J. Campagna, Barbara M. Jagodzinska, Dongwook Wi…·Varghese John
This paper identifies an APP-selective BACE1 inhibitor, FAH65, which shows substrate and enzyme selectivity, reduces Aβ levels, and improves cognitive performance in an AD mouse model.
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