Author

Chris Lawerenz

Berlin Institute of Health at Charité - Universitätsmedizin Berlin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:whole-genome sequencing· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Assay:DNA methylation· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Ivo BuchhalteriD· 2 shared Matthias SchlesneriD· 2 shared Adam P. Butler· 1 shared Agata WilkiD· 1 shared Alex Buchanan· 1 shared Ana Mijalkovic Lazic· 1 shared André KahlesiD· 1 shared Andy CafferkeyiD· 1 shared

Activity by Year

2017-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBioinformatics

Ivo BuchhalterORCID

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2 papers

Recent·Most cited

Pipeline Olympics: continuable benchmarking of computational workflows for DNA methylation sequencing data against an experimental gold-standard

Yu‐Yu Lin, Kersten Breuer, Dieter Weichenhan, Pascal Lafrenz, Antonella Sarnataro, Agata Wilk, Maryna Chepeleva, Oliver Mücke, Maximilian Schönung, Franziska Petermann, Philip Reiner Kensche, Lena Weiser, Frank Thommen, Gideon Giacomelli, Karl J. V. Nordström, , Pavlo Lutsik

The paper benchmarks DNA methylation sequencing workflows against an experimental gold-standard, identifying superior workflows and developing a sustainable benchmarking platform.

Nucleic Acids Research · Sep 12, 2025Peer-reviewedBioinformatics

Large-Scale Uniform Analysis of Cancer Whole Genomes in Multiple Computing Environments

Christina K. Yung, Brian D. O’Connor, Sergei Yakneen, Junjun Zhang, Kyle Ellrott, Kortine Kleinheinz, Naoki Miyoshi, Keiran M. Raine, Romina Royo, Gordon Saksena, Matthias Schlesner, Solomon I. Shorser, Miguel Vazquez, Joachim Weischenfeldt, Denis Yuen, , Charles L. Short

The paper describes the PCAWG project's large-scale analysis of cancer whole genomes across multiple computing environments, producing validated consensus variants for downstream research.

bioRxiv · Jul 10, 2017 · PreprintGenomics