Author
Wellcome Sanger Institute
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
Luca Barbon, Victoria Offord, Elizabeth J. Radford, Adam P. Butler, Sebastian S. Gerety, David J. Adams, Matthew E. Hurles, Hong Kee Tan, Andrew J. Waters
Bioinformatics · Nov 10, 2021Peer-reviewedGenomics
Bernardo Rodríguez–Martín, Eva G. Álvarez, Adrian Baez‐Ortega, Jorge Zamora, Fran Supek, Jonas Demeulemeester, Martín Santamarina, Young Seok Ju, Javier Temes, Daniel García Souto, Harald Detering, Yilong Li, Jorge Rodríguez‐Castro, Ana Dueso-Barroso, Alicia L. Bruzos, , the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Network
The paper analyzes somatic retrotransposition events in 2,954 cancer genomes, identifying L1 insertions as significant contributors to structural variations and oncogenesis.
bioRxiv · Sep 7, 2018 · PreprintGenomics
Francesco Iorio, Fiona M. Behan, Emanuel Gonçalves, Shriram G. Bhosle, Elisabeth D. Chen, Rebecca Shepherd, Charlotte Beaver, Rizwan Ahmad Ansari, Rachel Pooley, Piers Wilkinson, Sarah Harper, Adam P. Butler, Euan A. Stronach, Julio Sáez-Rodríguez, Kosuke Yusa, Mathew J. Garnett
CRISPRcleanR reduces false positives in CRISPR-Cas9 screens by correcting gene-independent responses without assuming copy number status.
BMC Genomics · Aug 13, 2018Peer-reviewedBioinformatics
Christina K. Yung, Brian D. O’Connor, Sergei Yakneen, Junjun Zhang, Kyle Ellrott, Kortine Kleinheinz, Naoki Miyoshi, Keiran M. Raine, Romina Royo, Gordon Saksena, Matthias Schlesner, Solomon I. Shorser, Miguel Vazquez, Joachim Weischenfeldt, Denis Yuen, , Charles L. Short
The paper describes the PCAWG project's large-scale analysis of cancer whole genomes across multiple computing environments, producing validated consensus variants for downstream research.
bioRxiv · Jul 10, 2017 · PreprintGenomics
Ivo Buchhalter, Barbara Hutter, Tyler S. Alioto, Timothy A. Beck, Paul C. Boutros, Benedikt Brors, Adam P. Butler, Sasithorn Chotewutmontri, Robert E. Denroche, Sophia Derdak, Nicolle Diessl, Lars Feuerbach, Akihiro Fujimoto, Susanne Gröbner, Marta Gut, , on behalf of the ICGC Verification and Validation Working Group
This study compares whole genome sequencing pipelines across five centers using a uniform tumor-normal sample pair, identifying factors affecting output consistency.
bioRxiv · Jun 12, 2015 · PreprintGenomics