Effects of bromodomain protein inhibition in a mouse model of Niemann-Pick type C disease
Martina Parente, Amélie Barthelemy, Sara Caputo, Noemie Charlery-Adele, Christian Galmiche, Claudia Tonini, Simona Lobasso, Danilo Prtvar, Sabina Tahirović, Sophie Reibel, Frank W. Pfrieger, Valentina Pallottini
This study investigates the effects of bromodomain protein inhibition in a mouse model of Niemann-Pick type C disease, finding sex-dependent therapeutic benefits in male mice.
bioRxiv · Jun 29, 2026 · PreprintNeuroscience