Christian Schwall

Mixed positive and negative feedback loops drive diverse single-cell gene expression dynamics

The paper uses stochastic modeling and experiments to show mixed feedback loops in bacteria generate diverse gene expression dynamics.

Environmental and molecular noise buffering by the cyanobacterial clock in individual cells

The paper shows how the cyanobacterial clock buffers noise through its core phosphorylation loop, using single-cell analysis and a stochastic model.

Tunable phenotypic variability through an autoregulatory alternative sigma factor circuit

The paper shows that the σV circuit in B. subtilis generates tunable phenotypic variability in response to stress, memory of previous stress, and genetic perturbations.

Escherichia coli can survive stress by noisy growth modulation

This study shows how E. coli uses noisy rpoS expression and growth modulation to survive oxidative stress through multi-generation rpoS pulses.