James C W Locke

This study shows that the plant heat shock regulatory network controls both the magnitude and distribution of stress-responsive gene expression across cells.

The paper uses stochastic modeling and experiments to show mixed feedback loops in bacteria generate diverse gene expression dynamics.

The paper develops a computational model of the wheat circadian oscillator to explain the altered timing of ELF3 expression compared to Arabidopsis.

This paper develops a mathematical model of bud-bud competition in Arabidopsis, showing that BRC1 modulates auxin efflux to influence bud competitiveness.

The paper shows how the cyanobacterial clock buffers noise through its core phosphorylation loop, using single-cell analysis and a stochastic model.

The paper investigates how nutrient availability affects the plasticity and invariance of inflorescence and floral meristems in Arabidopsis, showing differences in their response to nutrient changes.

The paper uses single-nucleus RNA-seq to construct an Arabidopsis SAM atlas, revealing transcriptional dynamics and regulatory elements during shoot stem cell differentiation.

This study uses single-cell time-lapse microscopy to show that RpoD4 pulses at cell division and links the circadian clock and cell cycle in Synechococcus elongatus.

The paper shows that the σV circuit in B. subtilis generates tunable phenotypic variability in response to stress, memory of previous stress, and genetic perturbations.

This study shows how E. coli uses noisy rpoS expression and growth modulation to survive oxidative stress through multi-generation rpoS pulses.

This study shows how the circadian clock and environmental cycles influence cell size control and division timing in cyanobacteria.

The paper examines single-cell circadian rhythms in Arabidopsis seedlings, revealing robust oscillations and spatial waves of gene expression that coordinate clock activity across the plant.