Matt Jones

This study identifies RPRD proteins as negative regulators of transcription in human cells, showing their inverse correlation with RNA accumulation and their role in forming complexes with Pol II.

The paper measures transcriptional bursting using Bayesian methods and shows that polymerase shuttling affects burst size and frequency, with implications for transcriptional noise.

The paper investigates how non-coding RNAs from the Prader-Willi syndrome locus regulate gene expression in human iPSCs, showing their role in neurodevelopmental processes.

This study shows how E. coli uses noisy rpoS expression and growth modulation to survive oxidative stress through multi-generation rpoS pulses.