A genetic variant alters the secondary structure of the lncRNA H19 and is associated with Dilated Cardiomyopathy
Leonie Martens, Frank Rühle, Anika Witten, Benjamin Meder, Hugo Albert Katus, Eloisa Arbustini, Gerd P Hasenfuss, Moritz F. Sinner, Stefan Kääb, Sabine Pankuweit, Christiane Angermann, Erich Bornberg‐Bauer, Monika Stoll
The paper identifies a SNP in lncRNA H19 that alters its secondary structure and is associated with Dilated Cardiomyopathy, suggesting structural changes in lncRNAs may explain hidden genetic variance.
RNA Biology · Jul 27, 2021Peer-reviewedGenetics