Author
German Centre for Cardiovascular ResearchORCID 0000-0002-6660-796XUnclaimed ORCID profile · follow to get notified of new preprints
7 papers
Recent·Most cited
Rebecca Keener, Surya B. Chhetri, Carla J. Connelly…·Alexis J. Battle
The paper validates novel telomere length regulation genes POP5 and KBTBD6 identified through trans-ancestry GWAS using functional experiments in blood cells.
Joshua S. Weinstock, Jayakrishnan Gopakumar, Bala Bharathi Burugula…·Rasika A. Mathias
The paper develops PACER to infer clonal expansion rates from single timepoint data and identifies TCL1A activation as a mediator of clonal hematopoiesis fitness.
Leonie Martens, Frank Rühle, Anika Witten…·Monika Stoll
The paper identifies a SNP in lncRNA H19 that alters its secondary structure and is associated with Dilated Cardiomyopathy, suggesting structural changes in lncRNAs may explain hidden genetic variance.
Margaret A. Taub, Matthew P. Conomos, Rebecca Keener…·Benjamin A. Raby
This study identifies 59 sentinel variants and two novel genes associated with telomere length using whole genome sequences from 109,122 trans-ethnic individuals.
Ιωάννα Ντάλλα, Lu-Chen C Weng, James Cartwright…·Dan M. Roden
This study identifies 210 genetic loci associated with the PR interval through multi-ancestry GWAS, highlighting their role in cardiac conduction and cardiovascular disease.
Jianan Zhana, CHARGE ECG Working Group, Jessica van Setten…·Steven Ron Cummings
This paper introduces SAPPHO methods to detect pleiotropy in GWAS by modeling shared patterns of genetic associations, finding 16 additional and 124 novel loci in meta-analysis.
Jessica van Setten, Jennifer A. Brody, Yalda Jamshidi…·Paolo Gasparini
This study identifies 47 novel genetic loci associated with PR interval through genome-wide association meta-analysis across multiple populations.