Transcriptional profiling of Multiple System Atrophy cerebellar tissue highlights differences between the parkinsonian and cerebellar sub-types of the disease
Ignazio Stefano Piras, Christiane Bleul, Isabelle Schrauwen, Joshua S. Talboom, Lorida Llaci, Matt D. De Both, Marcus Naymik, Glenda Margaret Halliday, Conceição Bettencourt, Janice L. Holton, Geidy E. Serrano, Lucia I. Sue, Thomas G. Beach, Nadia Stefanova, Matthew J. Huentelman
This study profiles RNA expression in MSA cerebellar tissue, identifying distinct transcriptional signatures between parkinsonian and cerebellar subtypes, with greater dysregulation observed in the cerebellar subtype.
Acta Neuropathologica Communications · Jun 3, 2020Peer-reviewedGenomics