Human cerebral organoids model tumor infiltration and migration supported by astrocytes in an autologous setting
Esther Schickel, Tamara Bender, Leon Kaysan, Simone Hufgard, Margot Mayer, David R. Grosshans, Christiane Thielemann, Insa S. Schroeder
This study develops a cerebral organoid model to study tumor infiltration and migration supported by astrocytes in an autologous setting, showing tumor-like cells exhibit invasive properties and are influenced by the glial environment.
bioRxiv · Jan 29, 2025 · PreprintCell Biology