Christina L Torturo

This study shows that early AAV FOXG1 gene therapy in female mice worsens motor behaviors, while it benefits males, highlighting gender-specific risks in potential human treatments.

This study shows that AAV FOXG1 gene therapy improves behavioral deficits in a mouse model of FOXG1 syndrome with a Q84P mutation.

This study assesses the robustness of Irwin tests across multiple sites for detecting drug-induced neurological effects in mice, finding reduced variability after protocol harmonization.