Author

Christopher DeGrave

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Ailing DuiD· 2 shared Christina L Torturo· 2 shared Dan WangiD· 2 shared Dinah W.Y. SahiD· 2 shared Jodi E. Gresack· 2 shared Kimberly Kerker· 2 shared Scott Reich· 2 shared Sylvie Ramboz· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

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2 papers

Recent·Most cited

Exacerbation of a Subset of Behavioral Phenotypes by Early Treatment with AAV FOXG1 Gene Replacement Therapy in a Mouse Model of FOXG1 Syndrome

Christina L Torturo, Kimberly Kerker, Jodi E. Gresack, Christopher DeGrave, Ailing Du, Dan Wang, Guangping Gao, Scott Reich, Sylvie Ramboz, Dinah W.Y. Sah

This study shows that early AAV FOXG1 gene therapy in female mice worsens motor behaviors, while it benefits males, highlighting gender-specific risks in potential human treatments.

bioRxiv · Oct 22, 2025 · PreprintNeuroscience

Behavioral Efficacy of AAV FOXG1 Gene Replacement Therapy in a Mouse Model of FOXG1 Syndrome

Christina L Torturo, Ailing Du, Kimberly Kerker, Jodi E. Gresack, Christopher DeGrave, Kathleen A. Funk, Princy Agnihotri, F. Hsieh, Teresa M. Gunn, Sylvie Ramboz, Brian R. Bettencourt, Scott Reich, Guangping Gao, Dan Wang, Dinah W.Y. Sah

This study shows that AAV FOXG1 gene therapy improves behavioral deficits in a mouse model of FOXG1 syndrome with a Q84P mutation.

bioRxiv · Apr 2, 2025 · PreprintNeuroscience