Loss of Frrs1l disrupts synaptic AMPA receptor function, and results in neurodevelopmental, motor, cognitive and electrographical abnormalities
Michelle E. Stewart, Petrina Lau, Gareth T. Banks, Rasneer Sonia Bains, Enrico Castroflorio, Peter L. Oliver, Christine L. Dixon, Michael C. Kruer, Dimitri Michael Kullmann, Abraham Acevedo‐Arozena, Sara E. Wells, Silvia Corrochano, Patrick M. Nolan
This study shows that loss of Frrs1l in mice causes reduced synaptic AMPA receptor levels, leading to motor, cognitive, and electrographical abnormalities.
Disease Models & Mechanisms · Jan 1, 2019Peer-reviewedNeuroscience