Peter L. Oliver

This study shows that silencing layer 6b neurons in mice alters theta frequency and EEG power during wake and sleep, and reduces orexin-induced wakefulness.

The paper develops ASO Atlas, a database of RNase H-mediated ASO sequences and their efficacy, and trains OligoAI, a deep learning model to predict ASO efficacy based on sequence and chemical features, reducing screening effort by 5.72-fold.

This study shows that loss of TDP-43 causes synaptic dysfunction through a cryptic exon in UNC13A, which is rescued by antisense oligonucleotides.

This study shows that loss of Frrs1l in mice causes reduced synaptic AMPA receptor levels, leading to motor, cognitive, and electrographical abnormalities.