Unc 51-like autophagy-activating kinase (ULK1) mediates clearance of free {alpha}-globin in {beta}-thalassemia
Christophe Lechauve, Julia Keith, Eugene Khandros, Stephanie Fowler, Kalin Mayberry, Abdullah Freiwan, Christopher S. Thom, Paola Delbini, Emilio Boada Romero, Jingjing Zhang, Irene Motta, Heather Tillman, M. Domenica Cappellini, Mondira Kundu, Mitchell J. Weiss
Rapamycin alleviates β-thalassemia by stimulating ULK1-dependent autophagy of toxic free α-globin.
bioRxiv · Oct 26, 2018 · PreprintCell Biology