Jingjing Zhang

This paper shows that mucosal mRNA vaccines protect against Kp pneumonia via Tc17 cells, not antibodies, and introduces an exosome platform enhancing vaccine efficacy.

The paper measures and predicts non-coding variant effects in human immune cells using single-cell ATAC-seq and whole-genome sequencing, revealing regulatory mechanisms and applications in systemic lupus erythematosus.

This study shows airway mRNA vaccines need better purification and sequence design to avoid dsRNA contaminants, leading to improved immune responses.

This study develops a genome-edited autologous CD34+ cell therapy to induce fetal hemoglobin for sickle cell disease, showing efficient editing, therapeutic HbF levels, and no off-target effects.

Rapamycin alleviates β-thalassemia by stimulating ULK1-dependent autophagy of toxic free α-globin.