Behavioral Efficacy of AAV FOXG1 Gene Replacement Therapy in a Mouse Model of FOXG1 Syndrome
Christina L Torturo, Ailing Du, Kimberly Kerker, Jodi E. Gresack, Christopher DeGrave, Kathleen A. Funk, Princy Agnihotri, F. Hsieh, Teresa M. Gunn, Sylvie Ramboz, Brian R. Bettencourt, Scott Reich, Guangping Gao, Dan Wang, Dinah W.Y. Sah
This study shows that AAV FOXG1 gene therapy improves behavioral deficits in a mouse model of FOXG1 syndrome with a Q84P mutation.
bioRxiv · Apr 2, 2025 · PreprintNeuroscience