CLUSTERING DYNAMICALLY MODULATE THE BIOPHYSICS OF VOLTAGE-GATED SODIUM CHANNELS: HOW NANOSCALE PHENOMENA DETERMINE HEALTH AND DISEASE
Mikhail Tarasov, Madison Ammon, Jan Otto Wirth, Christopher Hampton, Zoja Selimi, Rengasayee Veeraraghavan, Przemysław Radwański
The paper shows that clustering of voltage-gated sodium channels affects their biophysics, leading to different pharmacological responses and potential therapeutic implications.
bioRxiv · May 31, 2025 · PreprintPhysiology