Author

Christopher J. K. Wan

MRC Laboratory of Molecular Biology

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Biochemistry· 1

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Approach:experimental assay· 1

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Bryce E. CliftoniD· 1 shared Edoardo GianniiD· 1 shared Enrico Sandro ColizziiD· 1 shared James AttwateriD· 1 shared Kevin GoeijiD· 1 shared Philipp HolligeriD· 1 shared Samantha KwokiD· 1 shared

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Bryce E. CliftonORCID

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1 paper

Recent·Most cited

A polymerase ribozyme that can synthesize both itself and its complementary strand

Edoardo Gianni, Samantha Kwok, Christopher J. K. Wan, Kevin Goeij, Bryce E. Clifton, Enrico Sandro Colizzi, James Attwater, Philipp Holliger

The paper describes a ribozyme that can synthesize both itself and its complementary strand, suggesting polymerase ribozymes may be more common in RNA sequence space.

Science · Feb 12, 2026Peer-reviewedBiochemistry