Thienopyrimidine amide analogs target MmpL3 in Mycobacterium tuberculosis
Vanessa Pietrowski Baldin, Christopher L. Harding, Diana Quach, Joseph Sugie, Joe Pogliano, Tanya Parish
The paper identifies thienopyrimidine amides as MmpL3 inhibitors in M. tuberculosis, showing loss of potency in MmpL3 mutants and cell wall stress responses.
Antimicrobial Agents and Chemotherapy · Sep 22, 2025Peer-reviewedMicrobiology