Tanya Parish

This study identifies heterobenzamides as bacteriostatic agents against intracellular Mycobacterium tuberculosis by targeting QcrB, with limited activity against other pathogens.

This study identifies chlorotonils as potent anti-Mtb agents and shows resistance is mediated by MmpR5-MmpL5.

The paper identifies thienopyrimidine amides as MmpL3 inhibitors in M. tuberculosis, showing loss of potency in MmpL3 mutants and cell wall stress responses.

This study identifies common biological features of MmpL3 inhibitors, showing potent activity against M. tuberculosis and highlighting their potential as drug candidates.

The paper investigates an arylsulphonamide's mechanism against Mycobacterium tuberculosis, finding it targets cell wall biosynthesis via MmpL3.

The paper optimizes the DsRed fluorescent protein for expression in Mycobacterium tuberculosis and confirms its functionality with full-length constructs.