Molecular mimicry in deoxy-nucleotide catalysis: the structure of Escherichia coli dGTPase reveals the molecular basis of dGTP selectivity
Christopher O. Barnes, Ying Wu, Jinhu Song, Guowu Lin, Elizabeth L. Baxter, Aaron S. Brewster, Veeranagu Nagarajan, Andrew Holmes, Michael Soltis, Nicholas K. Sauter, Jinwoo Ahn, Aina E. Cohen, Guillermo Calero
This paper determines the structure of Escherichia coli dGTPase and elucidates the molecular basis of its dGTP selectivity through comparative analysis with SAMHD1.
bioRxiv · Nov 29, 2018 · PreprintBiophysics