PML nuclear bodies orchestrate the storage and degradation of aggregated HBc in the nucleus and reduce CAM-A-induced apoptosis.
V. Janovec, Laura Heydmann, Valério Taverniti, Christos Satratzemis, Jan Weber, Barbora Lubyová, Ivan Hirsch, Joachim Lupberger, Hannah Vanrusselt, Yannick Debing, Thomas F. Baumert, Eloi Rémi Verrier
This study shows that PML nuclear bodies store and degrade aggregated HBc, reducing apoptosis caused by CAM-A.
bioRxiv · Jun 29, 2026 · PreprintMicrobiology