Author

Christy Chang

University of Maryland, Baltimore

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 3 Genetic & Genomic Medicine· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 6 Approach:statistical model· 6 Research Focus:GWAS / association mapping· 5 Assay:whole-genome sequencing· 5 Research Focus:fine-mapping· 2 Research Focus:variant effect prediction· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Cara L. CartyiD· 6 shared Dimitrios AvramopoulosiD· 6 shared Jeffrey L. CurtisiD· 6 shared Joshua C. BisiD· 6 shared L. Adrienne CupplesiD· 6 shared Laura A. AlmasyiD· 6 shared Marcos BezerraiD· 6 shared Mark D. ChaffiniD· 6 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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6 shared papersGenomics

Cara L. CartyORCID

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6 papers

Recent·Most cited

Cross-cohort analysis of expression and splicing quantitative trait loci in TOPMed

Peter Orchard, Thomas W. Blackwell, Linda Kachuri, Peter J. Castaldi, Michael H. Cho, Stephanie A. Christenson, Peter Durda, Stacey Gabriel, Craig P. Hersh, Scott Huntsman, S.-J. Hwang, Roby Joehanes, Mari Johnson, Xingnan Li, Honghuang Lin, , Jeffrey L. Curtis

The paper analyzes expression and splicing quantitative trait loci (e/sQTL) across multiple tissues in the TOPMed dataset and finds that secondary e/sQTL signals are still discoverable, with many GWAS signals colocalizing with these e/sQTL.

Science · Jul 16, 2026Peer-reviewedGenetic & Genomic Medicine

Mosaic Loss of Y chromosome associates with lung function, emphysema and epigenetic aging

Woei‐Yuh Saw, Kangjin Kim, Yichen Huang, Jeong Hyun Yun, Xiaolong Ma, Jason Bacon, Yash Pershad, Daniel A Levy, George T. O’Connor, Eric Boerwinkle, R. Graham Barr, Stephen S. Rich, Jerome I. Rotter, April P. Carson, Laura M. Raffield, , Michael Rutledge DeBaun

This study investigates the association between mosaic loss of Y chromosome (mLOY) and lung function, emphysema, and epigenetic aging in men across multiple cohorts.

American Journal of Respiratory and Critical Care Medicine · Mar 19, 2026Peer-reviewedGenetic & Genomic Medicine

Whole-Genome Association Analyses of Sleep-disordered Breathing Phenotypes in the NHLBI TOPMed Program

Brian E. Cade, Jiwon Lee, Tamar Sofer, Heming Wang, Man Zhang, Han Chen, Sina A. Gharib, Daniel J. Gottlieb, Xiuqing Guo, Jacqueline M. Lane, Jingjing Liang, Xihong Lin, Hao Mei, Sanjay R. Patel, Shaun Purcell, , Scott E. Devine

The paper reports whole-genome association analyses of sleep-disordered breathing traits in the NHLBI TOPMed program, identifying rare and common variant associations.

Genome Medicine · Aug 26, 2021Peer-reviewedGenetics

Genome Sequencing Unveils a New Regulatory Landscape of Platelet Reactivity

Ali Reza Keramati, Ming‐Huei Chen, Benjamin A.T. Rodriguez, Lisa R. Yanek, Arunoday Bhan, Brady J. Gaynor, Kathleen A. Ryan, Jennifer A. Brody, Xue Yun Zhong, Qiang Wei, Namiko Abe, Gonçalo R. Abecasis, François Aguet, Christine M. Albert, Laura A. Almasy, , Paul S. de Vries

The paper uses whole genome sequencing to identify genetic loci associated with platelet aggregation, including novel variants in RGS18, SVEP1, and PEAR1.

Nature Communications · Jun 15, 2021Peer-reviewedGenomics

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

Pradeep Natarajan, Gina Marie Peloso, Seyedeh Maryam Zekavat, May E. Montasser, Andrea Ganna, Mark D. Chaffin, Amit V. Khera, Wei Zhou, Jonathan M. Bloom, J Engreitz, Jason Ernst, Jeffrey R. O’Connell, Sanni Ruotsalainen, Maris Alver, Ani W Manichaikul, , Sayantan Das

The paper analyzes whole genome sequences from 16,324 individuals to identify genetic variants associated with blood lipid levels and develops a polygenic score for LDL-C.

Nature Communications · Aug 17, 2018Peer-reviewedGenomics

Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

Seyedeh Maryam Zekavat, Sanni Ruotsalainen, Robert E. Handsaker, Maris Alver, Jonathan Bloom, Timothy Poterba, Cotton Seed, Jason Ernst, Mark D. Chaffin, J Engreitz, Gina Marie Peloso, Ani W Manichaikul, Chaojie Yang, Kathleen A. Ryan, Mao Fu, , Brian Custer

The paper uses whole genome sequencing to identify genetic variants associated with plasma lipoprotein(a) levels and finds high heritability and inter-ethnic differences in Lp(a) risk.

Nature Communications · Jun 28, 2018Peer-reviewedGenomics