Qiang Wei

This study develops a genetics-informed framework to repurpose drugs for type 2 diabetes, identifying telmisartan as a potential treatment based on GWAS data and EHR validation.

This paper introduces MSG, a method that integrates splicing data and GWAS summary statistics to identify trait-associated genes, showing improved power over existing methods.

The paper uses whole genome sequencing to analyze genetic diversity and selection in Guangxi indigenous chickens, identifying candidate genes under selection and population structure.

The paper identifies a structural variant associated with goat polledness through GWAS and CNV analysis, linking it to the ERG gene and providing insights into its molecular mechanisms.

The paper identifies a 582bp deletion upstream of LHX2 associated with cashmere production in goats through whole-genome sequencing and functional assays.

The paper uses whole genome sequencing to identify genetic loci associated with platelet aggregation, including novel variants in RGS18, SVEP1, and PEAR1.

DRAMS detects and corrects sample mix-ups in multi-omics data by aligning genetic and omics data, improving statistical power and result quality.