Mapping Allosteric Communication in the Nucleosome with Conditional Activity
Augustine C. Onyema, Chukwuebuka Dikeocha, Rutika Patel, Jonathan E. Moussa, Sharon M. Loverde
This paper uses molecular dynamics simulations and a new Python library to map allosteric communication in the nucleosome, identifying kinetically connected domains and dynamic coupling over long distances.
Journal of Chemical Information and Modeling · Feb 24, 2026Peer-reviewedBiophysics