The ENCODE Imputation Challenge: A critical assessment of methods for cross-cell type imputation of epigenomic profiles
Jacob Matthew Schreiber, Carles A. Boix, Jin wook Lee, Hongyang Li, Yuanfang Guan, Chun-Chieh Chang, Jen-Chien Chang, Alex Hawkins‐Hooker, Bernhard Schölkopf, Gabriele Schweikert, Mateo Rojas-Carulla, Arif Canakoglu, Francesco Guzzo, Luca Nanni, Marco Masseroli, , ENCODE Imputation Challenge Participants
The paper evaluates 23 imputation models for cross-cell type epigenomic data, finding quality assessment challenging due to distributional shifts, data availability, and redundant metrics.
Genome biology · Apr 18, 2023Peer-reviewedBioinformatics