Bidirectional Crosstalk Between Bladder Cancer Cells and Normal Fibroblasts Drives Phenotypic Reprogramming and Modulates Chemosensitivity
Jinhui Gao, Cindy Xinyu Ji, Ci Ren, John E.W. Hines, Eleanor Stride, Richard T. Bryan, Jennifer L. Rohn
This study shows that interactions between bladder cancer cells and normal fibroblasts drive phenotypic changes and affect chemotherapy response.
bioRxiv · Sep 9, 2025 · PreprintCancer Biology