Jennifer L. Rohn

This study evaluates how the urinary microenvironment and fluid flow affect antibiotic and phage therapy against UPEC, showing that physiological conditions reduce treatment efficacy.

This study evolves uropathogenic E. coli to fosfomycin resistance in a 3D bladder microtissue model and validates mutations in clinical isolates.

This study identifies neutrophil myeloperoxidase (MPO) as a biomarker for RSV severity and demonstrates its utility as a functional readout for evaluating antiviral therapies in an in vitro model.

This study investigates how gut-derived short-chain fatty acids affect uropathogenic Escherichia coli behavior and host-pathogen interactions at the colonic epithelial interface.

This study uses a 3D human urothelial model to compare microtrauma and adhesion caused by two catheter types, finding that an IAS-coated catheter causes less epithelial damage than a PVP-coated one.

This study shows that interactions between bladder cancer cells and normal fibroblasts drive phenotypic changes and affect chemotherapy response.

The paper introduces a 3D bladder cancer model in a human urothelial environment to better test cancer treatments and improve translational research.