Author

Clémence Penhoat

Inserm

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Pharmacology & Toxicology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

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Bernard FromentyiD· 1 shared Daniel CathelineiD· 1 shared Gregory Pinon· 1 shared Julie MassartiD· 1 shared Karima BegricheiD· 1 shared Vincent RiouxiD· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperPharmacology & Toxicology

Bernard FromentyORCID

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Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintNov 1, 2024

Fatty acid-mediated induction of CYP2E1 activity in HepaRG cells is not systematically associated with exacerbated acetaminophen cytotoxicity

Clémence Penhoat, Julie Massart, Gregory Pinon…·Karima Begriche

This study shows that increased CYP2E1 activity from fatty acids in HepaRG cells does not always lead to greater acetaminophen toxicity, as only certain fatty acids exacerbate liver damage.

DOI 10.1101/2024.11.01.621521

humanbulk RNA-seq

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