EXTRA-seq: a genome-integrated extended massively parallel reporter assay to quantify enhancer-promoter communication
Judith F. Kribelbauer-Swietek, Vincent Gardeux, Gerard Llimos, Kateřina Faltejsková, Julie Russeil, Nadia Grenningloh, Lucas Levassor, Clémence Steiner, Jiřı́ Vondrášek, Bart Deplancke
EXTRA-seq quantifies enhancer-promoter communication in endogenous contexts, revealing the TATA-box's role in modulating expression and improving gene expression prediction when integrated with deep learning models.
bioRxiv · Dec 8, 2024 · PreprintGenomics