MreC-MreD structure reveals a multifaceted interface that controls MreC conformation
Morgan S. A. Gilman, Irina Shlosman, Daniel D. Samé Guerra, Masy Domecillo, Elayne M. Fivenson, Claire Bourett, Thomas G. Bernhardt, Nicholas F. Polizzi, Joseph J. Loparo, Andrew C. Kruse
The paper determines the structure of MreC-MreD complex and shows how MreD controls MreC conformation, essential for bacterial cell shape and antibiotic targeting.
Proceedings of the National Academy of Sciences · Nov 3, 2025Peer-reviewedMicrobiology