Author

Daniel D. Samé Guerra

Harvard UniversityORCID 0000-0003-1128-7089Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Akshay Sankar· 2 shared Alexander Wang YingiD· 2 shared Cigall KadochiD· 2 shared João A. PauloiD· 2 shared Steven P. GygiiD· 2 shared Aasha M. Turner· 1 shared Ajinkya PatiliD· 1 shared Andrew C. KruseiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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2 shared papersMolecular Biology

Akshay Sankar

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3 papers

Recent·Most cited

Molecular BiologySciencePeer-reviewedJan 1, 2026

A SWI/SNF-specific Ig-like domain, SWIFT, is a transcription factor binding platform

Siddhant U. Jain, Kaylyn E. Williamson, Alexander Wang Ying…·Cigall Kadoch

The paper identifies SWIFT, a SWI/SNF subunit domain that mediates transcription factor interactions, showing its role in chromatin targeting and cancer cell proliferation.

11 citationstop 1%

humanChIP-seq

𝕏 PostBluesky

MicrobiologyProceedings of the National Academy of SciencesPeer-reviewedNov 3, 2025

MreC-MreD structure reveals a multifaceted interface that controls MreC conformation

Morgan S. A. Gilman, Irina Shlosman, Daniel D. Samé Guerra…·Andrew C. Kruse

The paper determines the structure of MreC-MreD complex and shows how MreD controls MreC conformation, essential for bacterial cell shape and antibiotic targeting.

7 citations

E. colicryo-EM

𝕏 PostBluesky

Molecular BiologyNature GeneticsPeer-reviewedOct 20, 2025

Shifted assembly and function of mSWI/SNF family subcomplexes underlie targetable dependencies in dedifferentiated endometrial carcinomas

Jessica D. St. Laurent, Grace Dydian Xu, Alexander Wang Ying…·Cigall Kadoch

This study identifies shifted mSWI/SNF subcomplex stoichiometry in DDEC/UEC cancers and shows that SMARCA4/2 inhibitors reduce tumor growth and synergize with chemotherapy.

4 citations

humanDNA methylation

𝕏 PostBluesky