Irina Shlosman

The paper determines the structure of MreC-MreD complex and shows how MreD controls MreC conformation, essential for bacterial cell shape and antibiotic targeting.

The paper develops a large yeast surface display library to identify high-affinity peptide ligands for various protein targets, revealing binding motifs and novel clones.

This study shows LpoB transiently binds and activates PBP1b through an allosteric switch, directing PG synthesis to low-density areas and enabling lipoprotein redistribution.