Immune disease variants modulate gene expression in regulatory CD4+ T cells and inform drug targets
Lara Bossini‐Castillo, Dafni A. Glinos, Natalia Kunowska, Gosia Golda, Abigail Lamikanra, Michaela Spitzer, Blagoje Soskic, Eddie Cano-Gamez, Deborah J. Smyth, Claire Cattermole, Kaur Alasoo, Alice Mann, Kousik Kundu, Nicole Soranzo, Ian Dunham, , Gosia Trynka
The paper identifies immune disease variants affecting Treg gene expression and highlights potential drug targets by linking GWAS signals with Treg QTLs.
bioRxiv · May 31, 2019 · PreprintGenetics