Author

Clare F. Hotze

Department of Chemistry and Biochemistry

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Biochemistry· 1

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Assay:cryo-EM· 1 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1 Organism:yeast· 1

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Darpan RaghaviD· 1 shared Nitesh Kumar Khandelwal· 1 shared Thomas M. TomasiakiD· 1 shared Tik Hang Soong· 1 shared

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1 shared paperBiochemistry

Darpan RaghavORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivJan 31, 2024

Structural Basis for Oxidized Glutathione Recognition by the Yeast Cadmium Factor 1

Tik Hang Soong, Clare F. Hotze, Darpan Raghav…·Thomas M. Tomasiak

The paper determines the cryo-EM structure of Ycf1 bound to oxidized glutathione and identifies a 'flex-pocket' mechanism for substrate binding and specificity.

DOI 10.1021/jacs.4c16335

yeastcryo-EM

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