Author

Claudia Moebius

Max Planck Institute of Molecular Cell Biology and Genetics

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Marc BickleiD· 3 shared Günter U. HöglingeriD· 2 shared Matthias HöllerhageiD· 2 shared Andreas Petzold· 1 shared Björn E. LangeriD· 1 shared Christian Wahl‐SchottiD· 1 shared Franziska HopfneriD· 1 shared Franziska RichteriD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersNeuroscience

Marc BickleORCID

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3 papers

Recent·Most cited

A genome-wide RNA interference screening reveals protectiveness of SNX5 knockdown in a Parkinson`s disease cell model

Matthias Höllerhage, Linghan Duan, Oscar Wing Ho Chua, Claudia Moebius, Svenja Bothe, Kristina Losse, Rebecca Kotzur, Kristina Lau, Franziska Hopfner, Franziska Richter, Christian Wahl‐Schott, Marc Bickle, Günter U. Höglinger

The paper identifies SNX5 knockdown as protective against alpha-synuclein toxicity in a Parkinson's disease cell model through genome-wide RNA interference screening.

Translational Neurodegeneration · Jun 2, 2025Peer-reviewedNeuroscience

Statistical integration of multi-omics and drug screening data from cell lines

Said el Bouhaddani, Matthias Höllerhage, Hae‐Won Uh, Claudia Moebius, Marc Bickle, Günter U. Höglinger, Jeanine J. Houwing‐Duistermaat

The paper presents a computational workflow integrating multi-omics and drug screening data from cell lines to identify druggable pathways in synucleinopathies.

PLoS Computational Biology · Jan 31, 2024Peer-reviewedBioinformatics

Phenotype loss is associated with widespread divergence of the gene regulatory landscape in evolution

Juliana G. Roscito, Katrin Sameith, Genı́s Parra, Björn E. Langer, Andreas Petzold, Claudia Moebius, Marc Bickle, Miguel Tréfaut Rodrigues, Michael Hiller

The paper shows that loss of morphological traits in snakes and subterranean mammals is linked to widespread divergence of regulatory elements associated with those traits.

Nature Communications · Nov 5, 2018Peer-reviewedGenomics