Author

Clayton Hutton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Carlos GuijasiD· 1 shared Cassandra L. Henry· 1 shared David A. Kummer· 1 shared Dylan M. Herbst· 1 shared Ellen M. Kozina· 1 shared Francisco J. Sarabia· 1 shared Holly T. ReardoniD· 1 shared Jacqueline L. Blankman· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Carlos GuijasORCID

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1 paper

Recent·Most cited

Base exchange inhibitors of SARM1 form mononucleotide adducts and activate SARM1 in vivo

Holly T. Reardon, Carlos Guijas, Jason R. Clapper, Julia A. Callender, Ellen M. Kozina, Francisco J. Sarabia, Clayton Hutton, Dylan M. Herbst, Taylor Andalis, Luka Perehinets, Cassandra L. Henry, Terry P. Lebold, David A. Kummer, Jacqueline L. Blankman, John J. M. Wiener, , Tarek A. Samad

The paper shows that SARM1 base exchange inhibitors form mononucleotide adducts and paradoxically activate SARM1, leading to increased cADPR and cADPR/NAD ratios in vivo.

bioRxiv · Apr 22, 2025 · PreprintNeuroscience